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PEA shields towards bacterial an infection by means of innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA at a dose of 0.1 mg/kg body excess weight extended survival level and diminished neuro-inflammation in an aged murine bacterial meningitis product, in the absence of antibiotics [forty two].1996). Oral PEA also
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2016a). This lesser raise was proportionate for the lesser peak of PEA concentrations detected in human volunteers in contrast with beagle dogs. This difference, consequently, is often brought on by the lessen complete quantity of PEA acutely administered to human volunteers (about ∼5 vs. 30 mg·kg−1 in puppies) and to The reality that this wa
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